STRUCTURE, FUNCTION AND REGULATION OF CYTOPLASMIC DYNEIN

Authors
SCHROER TA
Citation
Ta. Schroer, STRUCTURE, FUNCTION AND REGULATION OF CYTOPLASMIC DYNEIN, Current opinion in cell biology, 6(1), 1994, pp. 69-73
Citations number
39
Categorie Soggetti
Cytology & Histology
Journal title
Current opinion in cell biology → ACNP
ISSN journal
09550674
Volume
6
Issue
1
Year of publication
1994
Pages
69 - 73
Database
ISI
SICI code
0955-0674(1994)6:1<69:SFAROC>2.0.ZU;2-W
Abstract
Molecular cloning studies have provided valuable structural informatio n about the different subunits of cytoplasmic dynein and their relatio nships to their axonemal dynein counterparts. Recent unexpected findin gs regarding the role of this enzyme in mitosis have emerged from muta tional analyses and microinjection experiments, while studies of organ elle transport in vivo have revealed clues to mechanisms for physiolog ical regulation of dynein activity.