M. Arpin et al., MEMBRANE-ACTIN MICROFILAMENT CONNECTIONS - AN INCREASING DIVERSITY OFPLAYERS RELATED TO BAND-4.1, Current opinion in cell biology, 6(1), 1994, pp. 136-141
The cortical actin cytoskeleton participates in various membrane-based
processes which necessitate a large amount of plasticity in the molec
ular components involved in these interactions. A family of proteins h
omologous to band 4.1 is involved in the reorganization of the actin c
ytoskeleton in response to various stimuli, and probably plays a role
in transmembrane signalling. This family includes tyrosine phosphatase
s, substrates of tyrosine kinases and a candidate for a tumor-suppress
or gene.