Prosthetic rings are customarily used for mitral annuloplasty to plica
te and reinforce the annulus and keep the annulus from further dilatin
g. From July 1984 to March 1992, mitral annular plication using polyte
trafluoroethylene (PTFE) graft material was performed on 73 patients (
age range, 15 to 69 years; mean, 35.7 years) with mitral regurgitation
. The cause of the mitral regurgitation was rheumatic in 50.7% and deg
enerative in 36.9% of the patients. After other repair procedures on t
he mitral valve apparatus had been performed, a PTFE graft (3 mm) was
tailored to the length of the free edge of the anterior leaflet and th
en inserted at the posterior part of the mitral annulus between the co
mmissures. The operative mortality was 2.7%. Follow-up ranged from 0.7
to 8.5 years (mean, 5.6 years). Postoperative echocardiography confir
med that 94.2% of the survivors had either no or only mild mitral regu
rgitation with a large mitral valve area (2.7 +/- 0.3 cm(2)) and almos
t no pressure gradient across the mitral valve or left ventricular out
flow tract. Two patients successfully underwent redo PTFE mitral annul
oplasty. Two patients died, one 15 and the other 20 months later, due
to myocardial failure, with no mitral regurgitation. The event-free su
rvival rate was 90% +/- 4% at 8 years. We conclude that PTFE mitral an
nuloplasty is an effective procedure that yields good long-term result
s.