K. Thoren et al., LIPID EXTRACTED BANK BONE IMPLANTS IN THE ILIAC CREST EVALUATED BY CT, MRI AND BIOPSY, Journal of orthopaedic rheumatology, 6(4), 1993, pp. 141-149
During hip surgery on four patients with severe rheumatoid arthritis,
bank bone was used to refill the emptied iliac crest. The course of gr
aft incorporation was followed by CI, MRI and biopsies. In the first t
hree cases, biopsies were taken after 3, 6 and 12 months respectively.
Since the results indicated a process of incorporation which would pr
obably be detectable by MRI, we designed a meticulous follow up on a f
ourth patient. Repeated axial projections with Cr and MRI were perform
ed at 0.5, 3, 6, 12 and 18 months after the operation. CT demonstrated
a higher density corresponding to the size and shape of the implanted
graft. MRI indicated initial oedema, but within 1 year the signals ch
anged to that of normal marrow. At 6 months, contrast infusion of Gd-D
TPA confirmed blood perfusion in the graft. The 12 month biopsy in thi
s patient showed full incorporation. This patient also received oxytet
racycline preoperatively, and the biopsy showed tetracycline labelling
throughout. The results support the use of lipid extracted bank bone
in the iliac crest to produce new autografts for future use. MRI, espe
cially in combination with CT, could be a useful clinical tool to moni
tor graft incorporation.