LOCAL INFILTRATION OF EPINEPHRINE AND BUP IVACAINE IN TONSILLECTOMY

The effects of peritonsillar injections of epinephrine and local anest hetics before tonsillectomy on blood loss and postoperative pain were evaluated in a prospective, randomized double-blind trial on 103 child ren. Patients were randomly as signed into one of three groups: contro ls given injections of 0.9% NaCl (n=34), patients injected with 0.4 ml /kg (1:200,000) epinephrine combined with 0.25% bupivacaine (n=33) and patients given only 1:200,000 epinephrine (n=36). All injections and operations were performed by the same surgeon (KS). Blood loss was cal culated by weighing all blood aspirated perioperatively and swabs used during surgery. Postoperative pain was assessed at regular intervals by using three methods: (1) use of a visual analogue scale by parents and nurses to estimate pain; (2) postoperative need for nalbuphin as a nalgesic; (3) the Hannallah-Broadman semi-objective pain score (includ ing crying, anxiety, restlessness, and changes in blood pressure). The mean blood loss in the control group (given Na Cl) was 132 g, which w as significantly increased when compared with the epinephrine/bupivaca ine group (85 g) and the group treated with only epinephrine (90 g). H owever, analysis of the postoperative pain scores did not reveal any s ignificant differences among groups. These findings indicate that the peritonsillar injection of bupivacaine does not decrease postoperative pain, but peritonsillar injections of epinephrine will significantly reduce blood loss during tonsillectomy.