SEQUENCES OF MEMORY-GUIDED SACCADES IN PARKINSONS-DISEASE

Authors
VERMERSCH AI RIVAUD S VIDAILHET M BONNET AM GAYMARD B AGID Y PIERROTDESEILLIGNY C
Citation
Ai. Vermersch et al., SEQUENCES OF MEMORY-GUIDED SACCADES IN PARKINSONS-DISEASE, Annals of neurology, 35(4), 1994, pp. 487-490
Citations number
14
Categorie Soggetti
Clinical Neurology",Neurosciences
Journal title
Annals of neurology → ACNP
ISSN journal
03645134
Volume
35
Issue
4
Year of publication
1994
Pages
487 - 490
Database
ISI
SICI code
0364-5134(1994)35:4<487:SOMSIP>2.0.ZU;2-F
Abstract
Sequences of ocular saccades were studied in 8 patients with Parkinson 's disease, with (i.e., ''on'') and without (i.e., ''off'') levodopa t reatment. The amplitude of single saccades was decreased and not impro ved by treatment. The chronology of saccades during sequences was impa ired in patients in the ''off'' state, but significantly improved duri ng the ''on'' period. These results are compatible with a decreased ac tivation of the supplementary motor area, which can be reversed by lev odopa.