RETROGRADE EJACULATION AND LOSS OF EMISSION - POSSIBILITIES OF CONSERVATIVE TREATMENT

Twenty-five patients with retrograde ejaculation/loss of emission were treated with ephedrine sulfate or imipramine hydrochloride. Seventeen of them suffering from both diabetes and retrograde ejaculation were treated with ephedrine or, in case that ephedrine failed to convert re trograde ejaculation into anterograde ejaculation, with imipramine. Po sitive results were obtained in 5/17 (29.3%) patients, i.e. in 3 (17.6 %) and 2 (11.7%) patients on ephedrine and imipramine, respectively. T he daily dose of ephedrine was 50 mg and that of imipramine 75 mg, dur ing a 4-week period. In the group with retroperitoneal lymphadenectomy , after treatment with ephedrine, only 1 (12.5%) had retrograde ejacul ation while the remaining patients (n = 7) continued to lack semen emi ssion. These 7 patients were treated with imipramine, and 3 of them (4 2.8%) achieved anterograde ejaculation. In one third of patients with retroperitoneal lymphadenectomy and diabetes, with retrograde ejaculat ion or loss of semen emission, conservative treatment can offer improv ement or conversion to anterograde ejaculation.