Vs. Gurevich et al., ALTERATIONS IN PLATELET FUNCTIONAL-ACTIVI TY IN PATIENTS WITH ANGINA-PECTORIS DURING COLD TEST, Kardiologia, 32(9-10), 1992, pp. 54-57
The functional activity of platelets was examined in patients with cor
onary heart disease and healthy individuals during cold test (CT). Pat
ients prone to vasospastic responses to CT exhibited platelet activati
on along with beta-thromboglobulin release and formation of spontaneou
s platelet aggregates. Comparison of functional changes in platelet fu
nctional activity which occurred during cold test and intravenous ergo
metrine test suggest that the response to CT may be substantially high
er if platelet aggregability is concurrently determined. The unidirect
ional changes in platelet aggregability during cold and ergometrine te
sts in patients with signs of dynamic coronary occlusion may indicate
a relation of platelets with coronary vasoconstriction.