Es. Paykel et al., INCIDENCE OF DEMENTIA IN A POPULATION OLDER THAN 75 YEARS IN THE UNITED-KINGDOM, Archives of general psychiatry, 51(4), 1994, pp. 325-332
Background: Incidence studies have been relatively neglected in psychi
atric epidemiology. They are particularly important for dementia, sinc
e prevalence rates are affected by length of survival, which itself fa
lls with increasing age and presence of dementia. Methods: Two-wave co
mmunity study of 1195 elderly subjects aged older than 75 years, restu
died 2.4 years after a community prevalence study. A two-stage method
was used, comprising the Mini-Mental State Examination followed in a s
tratified sample by the Cambridge Examination for Mental Disorders of
the Elderly (CAMDEX) interview. Incidence rates were based on person-y
ears at risk. Results: Annual incidence rates for dementia were 2.3% f
or subjects initially aged 75 to 79 years, 4.6% for ages 80 to 84 year
s, and 8.5% for ages 85 to 89 years, approximately doubling every 5 ye
ars. Rates did not differ significantly by sex, educational level, or
social class. Twice as many additional individuals received a diagnosi
s of minimal dementia not reaching case threshold. Conclusions: The fi
ndings show high rates of new onset dementia, increasing markedly with
age, and suggest rapid acceleration of one or more processes that is
common in advanced age.