A COMPARISON OF 2 ANTECUBITAL FOSSA TESTS WITH PERSONAL CARE PRODUCTS

Two antecubital wash protocols were compared by testing a syndet bar a nd a moisturizer. The results show that the irritation potential predi cted for a material is highly dependent on the conditions under which it is tested. It is possible to generate irritation far in excess of w hat would be expected under normal use, even for a product with skin-h ealing effects, by using aggressive exposure conditions. The results h ighlight a need to employ exposures representative of the anticipated use conditions and to interpret results in the context in which they a re generated to avoid drawing incorrect conclusions about a material's in-use irritancy.