Several diagnostic assays designed for rapid and accurate diagnosis of
rotavirus infection have been developed and effectively used in food
animal enteritis cases. Most of the seven currently recognized groups
of rotavirus are major pathogens in both human and food animal neonate
s; some groups have become important in adult diarrhea outbreaks. Stim
ulation of local enteric immunity is required to combat infection effe
ctively. Quantitation of serum antibody during assessment of the true
protective ability of passively acquired (or actively induced) immunit
y still provides some measure of protection because the antibody reloc
ates to the gut after neonatal enteric absorption. This article review
s diagnostic approaches currently used to identify rotavirus infection
. Strategies for passive and vaccinal protection that have been used t
o manage rotavirus enteritis in food animals are also discussed.