LOCAL GAS HOLD-UP IN XANTHAN-GUM-SIMULATED ACTINOMYCES MEDIA IN A STIRRED BIOREACTOR

Authors
VLAEV SD VALEVA M
Citation
Sd. Vlaev et M. Valeva, LOCAL GAS HOLD-UP IN XANTHAN-GUM-SIMULATED ACTINOMYCES MEDIA IN A STIRRED BIOREACTOR, Biotechnology techniques, 8(3), 1994, pp. 149-152
Citations number
7
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology techniques → ACNP
ISSN journal
0951208X
Volume
8
Issue
3
Year of publication
1994
Pages
149 - 152
Database
ISI
SICI code
0951-208X(1994)8:3<149:LGHIXA>2.0.ZU;2-O
Abstract
The distribution of gas hold-up in pseudoplastic xanthan-gum media, as prepared to mimic bioreactor states formed in the time-course of ferm entation of Streptomyces fradiae during the antibiotic production of T ylosin, is studied. Cases of gas maldistribution at high viscosity, su ch as very low gas concentration near the vessel wall and relatively h igh gas concentration near the vessel axis, which reveal flow deficien cies, such as gas channelling and flow stagnancy, are registered and q uantified.