Simple and accurate detection of microsatellite polymorphisms became a
n important tool in linkage analysis, gene mapping and DNA typing. Flu
orescent labeling of PCR products enabled fast and accurate typing of
a large number of individuals using an automated laser fluorescence DN
A sequencer. An other simple possibility for the detection of microsat
ellite polymorphisms is rapid silver staining of non labeled PCR produ
cts separated in native PAA gels.