IMPROVED SYNTHESIS OF TRIFLUOROMETHYL SULFONES USED AS INTERMEDIATES FOR THE PREPARATION OF DISUBSTITUTED OR TRI-SUBSTITUTED OLEFINS

Authors
EUGENE F LANGLOIS B LAURENT E
Citation
F. Eugene et al., IMPROVED SYNTHESIS OF TRIFLUOROMETHYL SULFONES USED AS INTERMEDIATES FOR THE PREPARATION OF DISUBSTITUTED OR TRI-SUBSTITUTED OLEFINS, Journal of fluorine chemistry, 66(3), 1994, pp. 301-309
Citations number
44
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Journal of fluorine chemistry → ACNP
ISSN journal
00221139
Volume
66
Issue
3
Year of publication
1994
Pages
301 - 309
Database
ISI
SICI code
0022-1139(1994)66:3<301:ISOTSU>2.0.ZU;2-V
Abstract
Primary and secondary trifluoromethyl sulfones (triflones) are efficie ntly obtained from easily available sodium trifluoromethanesulfinate ( triflinate) and alkyl bromides in N, N-dimethylacetamide. This techniq ue is more powerful than the potassium triflinate/acetonitrile system. Ethyl aconitate can be also produced in one step from ethyl bromoacet ate and diisopropylethylamine, sodium triflinate being a catalyst.