Ty. Wong et Mc. Mihm, ACANTHOLYTIC DERMATOSIS LOCALIZED TO GENITALIA AND CRURAL AREAS OF MALE-PATIENTS - A REPORT OF 3 CASES, Journal of cutaneous pathology, 21(1), 1994, pp. 27-32
A series of 3 cases of acantholytic dermatosis localized to the male g
enitalia and perineal area with distinct clinical and histological fea
tures is presented. These patients did not have a family history of si
milar disorders and had no evidence of rash elsewhere. Clinically, the
eruption was characterized by multiple discrete papules or macerated
patches involving the genitalia and the perineum. Histologically, the
acantholytic dermatosis had features that resembled both Hailey-Hailey
disease and Darier's disease. Similar clinical and histological findi
ngs have been reported in females. To the best of our knowledge, this
is the first report of these lesions described confined to the genital
and perineal areas in male patients. We agree with other authors that
this condition may represent a distinct acantholytic eruption in the
perineal area that should be distinguished from other generalized blis
tering acantholytic dyskeratotic disorders that may also involve the g
enitalia.