Recent progress in studies of antisweet substances, sweet proteins and
sweetness-inducing proteins is reviewed. Gymnemic acid, ziziphin and
hodulcin, which are triterpene glycosides, suppress the sweet taste se
nsation in humans, and gurmarin, which is a peptide, suppresses the sw
eet taste response in the rat. Five sweet proteins, monellin, thaumati
n, pentadin, curculin and mabinlin, are known. There are two sweetness
-inducing proteins. Miraculin has the ability to modify a sour taste i
nto a sweet taste. Curculin, which is itself a sweet protein, induces
a sweet taste in response to water, as well as having a taste-modifyin
g activity similar to that of miraculin.