The ultrasound contrast medium obtained by the original methods was ad
ministered into the left ventricular cavity and myocardium of 12 open-
chest dogs by using a catheter. After its administration into the cavi
ty there was its intensive contrast. When the ultrasound contrast was
administered into the aortic root, the entire myocardium contrasted, o
n selective administrations of the contrast into the coronary arteries
, the beds supplied by appropriate arteries contrasted. The ultrasound
contrast study enabled the areas with impaired perfusion as echo-nega
tive ''filling defects'' to be detected and mapped. The imaging of myo
cardial blood flow in tomographic sections and real time allows one to
regard it promising for clinical use.