The antiarrhythmic efficacy of the anticonvulsant sodium valproate was
studied in 22 patients with ventricular premature contraction in the
immediate (10-15 days) and late (2-5 months) periods of therapy. The p
rolong antiarrhythmic effect of the drug was observed in 66 % of the p
atients in whom it was beneficial in the first days of therapy. The re
sults obtained provide strong evidence for the efficacy of sodium valp
roate in patients with ventricular premature contraction occurring in
the presence of neurocirculatory dystonia.