REVEALING RISK-FACTORS FOR HEMODYNAMIC DI SADAPTATION DURING EXERCISEAS EVIDENCED BY GENETIC-STUDIES .1.

Twenty eight pairs of unisexual healthy twins were examined during exe rcise, on anapriline or their combination. The twin technique of calcu lating the additive component of blood pressure and catecholamine leve ls was used in each of the terms of the examination. Beta-adrenoceptor blockade was found to be a highly potent environmental factor under w hose influence both resting and exercise blood pressures were not prov ided by inheritable regulatory mechanisms. The latter resulted in tens e synthetic function of the sumpathoadrenal system and in disadaptatio n of the cardiovascular system when anapriline and exercise were used, which might serve an individual prognostic criterion of exercise tole rance.