COMPARATIVE-ANALYSIS OF THE ANTIARRHYTHMI C ACTION AND ELECTROPHYSIOLOGICAL EFFECTS OF THE NEW BENZODIAZEPIN DERIVATIVE GIDAZEPAM AND ETHACIZINE IN CARDIAC-ARRHYTHMIAS OF VARIOUS GENESIS

Authors
SKIBITSKY VV PETROVA TR KANORSKY SG
Citation
Vv. Skibitsky et al., COMPARATIVE-ANALYSIS OF THE ANTIARRHYTHMI C ACTION AND ELECTROPHYSIOLOGICAL EFFECTS OF THE NEW BENZODIAZEPIN DERIVATIVE GIDAZEPAM AND ETHACIZINE IN CARDIAC-ARRHYTHMIAS OF VARIOUS GENESIS, Kardiologia, 32(6), 1992, pp. 35-37
Citations number
11
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
Kardiologia → ACNP
ISSN journal
00229040
Volume
32
Issue
6
Year of publication
1992
Pages
35 - 37
Database
ISI
SICI code
0022-9040(1992)32:6<35:COTACA>2.0.ZU;2-Y
Abstract
The antiarrhythmic and electrophysiological effects of the new benzodi azepin tranquilizer gidazepam versus ethacizine were examined in patie nts with cardiac arrythmias. The antiarrhythmic effect of the agent wa s found during 24-day monitoring and simulated psychoemotional stress in 81 % of patients with neurocirculatory dystonia and in 61 % of pati ents with coronary heart disease. The antiarrhythmic effects developed with gidazepam-induced changes in electrophysiological properties of the cardiac conduction system. The preventive antiarrhythmic effect of gidazepam was demonstrated to be higher than that of ethacizine durin g stress in patients with arrhythmias of extraischemic genesis.