EFFECT ON FOOD-INTAKE AND BODY-WEIGHT OF LESIONS IN AND ADJACENT TO THE POSTERODORSAL AMYGDALA IN RATS

Bilateral lesions centered in the posterodorsal amygdala of female rat s resulted in hyperphagia and excessive weight gain. The brain damage extended posteriorly through the amygdalohippocampal area and into the ventral hippocampus and subiculum. Lesions centered in the ventral hi ppocampal formation had a less pronounced, although still significant, effect on body weight. Damage to large areas of the amygdala, includi ng the anterior, basolateral, and corticomedial groups of nuclei, was without effect. A serial reconstruction of overlapping areas of destru ction for both effective and ineffective lesions is presented.