CONCISE SYNTHESIS OF 7,8-DIMETHOXYISOCHROMAN-3-ONE - FORMAL SYNTHESISOF BERBERINE

Authors
ISHII H OZAWA M OHTA S HARAYAMA T ISHIKAWA T
Citation
H. Ishii et al., CONCISE SYNTHESIS OF 7,8-DIMETHOXYISOCHROMAN-3-ONE - FORMAL SYNTHESISOF BERBERINE, Heterocycles, 37(2), 1994, pp. 897-902
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
37
Issue
2
Year of publication
1994
Pages
897 - 902
Database
ISI
SICI code
0385-5414(1994)37:2<897:CSO7-F>2.0.ZU;2-9
Abstract
7, 8-Dimethoxyisochroman-3-one (2), a synthetic precursor for berberin e, was concisely synthesized from 4-formyl-7-methoxy-2-methylbenzo[b]f uran (3), which had been readily available from isovanillin through th e CsF-mediated Claisen rearrangement of the corresponding propargyl et her.