CHROMOSOMAL LOCALIZATION OF THE CALLIPYGE GENE IN SHEEP (OVIS-ARIES) USING BOVINE DNA MARKERS

Citation
Ne. Cockett et al., CHROMOSOMAL LOCALIZATION OF THE CALLIPYGE GENE IN SHEEP (OVIS-ARIES) USING BOVINE DNA MARKERS, Proceedings of the National Academy of Sciences of the United Statesof America, 91(8), 1994, pp. 3019-3023
Citations number
28
Categorie Soggetti
Multidisciplinary Sciences
ISSN journal
00278424
Volume
91
Issue
8
Year of publication
1994
Pages
3019 - 3023
Database
ISI
SICI code
0027-8424(1994)91:8<3019:CLOTCG>2.0.ZU;2-3
Abstract
A mutation causing muscular hypertrophy, with associated leanness and improved feed efficiency, has been recently identified in domestic she ep (Ovis aries). Preliminary results indicate that an autosomal domina nt gene may be responsible for this economically advantageous trait. W e have exploited the conservation in sequence and chromosomal location of DNA markers across Bovidae to map the corresponding callipyge locu s to ovine chromosome 18 using a battery of bovine chromosome 21 marke rs. Chromosomal localization of the ovine callipyge locus is the first step toward positional cloning of the corresponding gene.