The impact of antioxidative therapy with dibunol on the clinical cours
e of an arrhythmic type of alcoholic damage was studied. A total of 20
patients with Stage II chronic alcoholism (mean age 38.1 +/- 1.9 year
s) and ventricular premature contraction were examined. The diagnosis
of cardiac alcoholic damage was established after comprehensive studie
s. The effects of dibunol on the pattern of ventricular arrhythmias we
re tested by 24-hour Holter monitoring: control, on days 10 and 20 of
therapy. The daily dosage of dibunol was 20 mg per kg body weight. The
results of studies suggest that dibunol exerts a beneficial effect on
the clinical course of the disease and the nature of ventricular arrh
ythmias by reducing the number of ventricular extrasystoles by 51.4%.