ANTIOXIDATIVE THERAPY IN ARRHYTHMIC TYPE OF ALCOHOLIC DAMAGE TO THE HEART

The impact of antioxidative therapy with dibunol on the clinical cours e of an arrhythmic type of alcoholic damage was studied. A total of 20 patients with Stage II chronic alcoholism (mean age 38.1 +/- 1.9 year s) and ventricular premature contraction were examined. The diagnosis of cardiac alcoholic damage was established after comprehensive studie s. The effects of dibunol on the pattern of ventricular arrhythmias we re tested by 24-hour Holter monitoring: control, on days 10 and 20 of therapy. The daily dosage of dibunol was 20 mg per kg body weight. The results of studies suggest that dibunol exerts a beneficial effect on the clinical course of the disease and the nature of ventricular arrh ythmias by reducing the number of ventricular extrasystoles by 51.4%.