PHARMACOTHERAPY OF VERTIGO - ANY NEWS TO BE EXPECTED

Despite the introduction of new medicinal agents for the treatment of vertigo, no new pharmacological entities have been established. For se veral years all ''new'' products have belonged to the well established pharmacological classes of antihistamines (H-1-antagonists), calcium- entry inhibitors or vasodilators. In this article these pharmacologica l classes will be briefly reviewed, with special emphasis given to the pre-synaptic histamine receptor (H,), a recently established pharmaco logical function. Compounds interfering with this receptor, especially the antagonists, seem to offer new ways of treating vertigo and possi bly also new ways of developing new therapeutic agents.