Mj. Odonnell et al., A NEW ACTIVE CATALYST SPECIES FOR ENANTIOSELECTIVE ALKYLATION BY PHASE-TRANSFER CATALYSIS, Tetrahedron, 50(15), 1994, pp. 4507-4518
This paper briefly reviews the use of Schiff base substrates in amino
acid synthesis. Recent studies lead to the proposal of a new active ca
talyst species (12) for the asymmetric PTC alkylation of active methyl
ene compounds (2). Mechanistic implications are detailed.