STEREOSPECIFIC SYNTHESIS OF NEW CHIRAL ACYCLIC GUANINE NUCLEOSIDE ANALOGS

Authors
ELKATTAN Y GOSSELIN G IMBACH JL
Citation
Y. Elkattan et al., STEREOSPECIFIC SYNTHESIS OF NEW CHIRAL ACYCLIC GUANINE NUCLEOSIDE ANALOGS, Bulletin de la Societe chimique de France, 131(2), 1994, pp. 118-120
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear",Biology,Chemistry
Journal title
Bulletin de la Societe chimique de France → ACNP
ISSN journal
00378968
Volume
131
Issue
2
Year of publication
1994
Pages
118 - 120
Database
ISI
SICI code
0037-8968(1994)131:2<118:SSONCA>2.0.ZU;2-4
Abstract
Hitherto unknown 2',3'- and 3',4'-seco-nucleosides 10 and 14 that reta in the carbon framework of guanosine but have a hydroxymethyl substitu ent on the 4' or 5' position have been synthesized by ring opening of a suitably protected 9-beta-D-galactopyranosyl guanine 5.