ANGIOGENESIS - A NEW DIAGNOSTIC ASPECT OF OBSTETRIC AND GYNECOLOGIC ECHOGRAPHY

An ultrasounds triplex system (pulsed Doppler, Color mode, B mode) has been employed to study ovarian and uterine circulatory changes in fer tile, infertile and postmenopausal patients. PI and mean percentage va riation of PI mean values have been used. No difference has been detec ted in uterine haemodynamics between fertile women and those infertile patients getting pregnant by IVF-ET procedure. Patients who did not o btain the pregnancy showed different uterine and endometrial Color Dop pler patterns. Furthermore, a typical endometrial blood flow has been detected both in fertile patients and infertile patients who get pregn ant. Color Doppler seems to be an useful tool in the monitoring of fib roids blood supply and the uterine blood supply, especially for the cl inical monitoring of GnRH analogues therapies. The technique has been also employed for the study of ectopic pregnancy. The evaluation of bo th uterine and throphoblast haemodynamics has resulted in a good indic ator of the pregnancy progression. Concerning the ovarian pathology th e color Doppler evaluation has been useful to differentiate ovarian ma lignant cysts from inflammatory or disfunctional masses. Nevertheless, the most interesting results have been obtained from the study of end ometrial and ovarian tumors. Indeed, in the most cases, a mass supply blood flow has been detected, although in some cases no angiogenetic c olor flow has been found. No difference has been found in uterine arte ry velocimetry between malign or benign pathologies. Furthermore, hist ological data supporting our findings are presented.