THE METHYLATION OF ARSENATE BY A MARINE ALGA POLYPHYSA-PENICULUS IN THE PRESENCE OF L-METHIONINE-METHYL-D(3)

Authors
CULLEN WR LI H PERGANTIS SA EIGENDORF GK HARRISON LG
Citation
Wr. Cullen et al., THE METHYLATION OF ARSENATE BY A MARINE ALGA POLYPHYSA-PENICULUS IN THE PRESENCE OF L-METHIONINE-METHYL-D(3), Chemosphere, 28(5), 1994, pp. 1009-1019
Citations number
39
Categorie Soggetti
Environmental Sciences
Journal title
Chemosphere → ACNP
ISSN journal
00456535
Volume
28
Issue
5
Year of publication
1994
Pages
1009 - 1019
Database
ISI
SICI code
0045-6535(1994)28:5<1009:TMOABA>2.0.ZU;2-H
Abstract
Polyphysa peniculus growing in artificial seawater methylates arsenate to produce a dimethylarsenic derivative, probably dimethylarsinate. W hen L-methionine-methyl-d3 is added to the culture the CD3 label is in corporated intact in the dimethylarsenic compound to a considerable ex tent, indicating that S-adenosylmethionine, or some related sulphonium compound, is involved in the biological methylation. Conclusive evide nce of the CD3 incorporation was provided by using a specially develop ed hydride generation-gas chromatography-mass spectrometry methodology .