PREVALENCE OF MAIN RISK-FACTORS AMONG PRO BANDS WITH A HISTORY OF EARLY MYOCARDIAL-INFARCTION AND THEIR RELATIVES (ACCORDING TO FAMILY REGISTERS IN BISHKEK AND NOVOSIBIRSK)

Macrofocal or transmural myocardial infarction at the age under 50 in probands served the criterion for selection of 136 families in Bishkek and Novosibirsk (66 Kirghiz and 70 Russian families, respectively). M ain risk factors in probands and their families were determined accord ing to WHO methodological recommendations. Essential hypertension was more prevalent in probands and their families in Bishkek, while hyperc holesterolemia was more common in Novosibirsk families. Smoking was do cumented in Bishkek and Novosibirsk probands in equal proportions, tho ugh there were more smokers among probands' sons in Bishkek. Overweigh t occurred with equal frequency in probands' wives and daughters in bo th cities, but in probands and their sons in Novosibirsk this risk fac tor appeared more prevalent. Novosibirsk cases of reduced levels of hi gh-density lipoproteins cholesterol and triiodothyronine, elevated con centrations of apolipoprotein B and immunoreactive insulin outnumbered those in Bishkek.