To what extent are the empirical regularities implied by market micros
tructure theories useful in predicting the short-run behavior of stock
returns? A two-equation econometric model of quote revisions and tran
saction returns is developed and used to identify the relative importa
nce of different microstructure theories and to make predictions. Micr
ostructure variables and lagged stock index futures returns have in-sa
mple and out-of-sample predictive power based on data observed at five
-minute intervals. The most striking microstructure implication of the
model, confirmed by the empirical results, specifies that the expecte
d quote return is positively related to the deviation between the tran
saction price and the quote midpoint while the expected transaction re
turn is negatively related to the same variable.