OBJECTIVE: To report a suicide attempt with an aspirin enema. CASE SUM
MARY: A patient presented to the emergency room after self-administeri
ng, in enema form, approximately 700 aspirin tablets dissolved in wate
r. Over the next 12 hours the patient became progressively acidemic wi
th eventual cardiac arrest and subsequent chronic hypoxic encephalopat
hy. DISCUSSION: This patient's poor outcome was the result of retained
aspirin products in the rectal vault combined with the failure to rec
ognize the delayed absorption properties of rectally administered aspi
rin. CONCLUSIONS: In rectal aspirin overdoses, aspirin absorption from
the rectum may occur over a long period of time. It is important to r
emove as much aspirin from the rectum as possible and to closely monit
or these patients so that appropriate therapy may be started quickly.
Activated charcoal given both in enema and oral form may help decrease
aspirin absorption. Hemodialysis should be available and performed wi
thout delay should the patient require it.