M. Breitenseher et al., COLOR DOPPLER SONOGRAPHY OF RENAL-ALLOGRA FTS - IS THE RESISTIVE INDEX A DIAGNOSTIC-TOOL IN THE LONG-TERM FOLLOW-UP, Ultraschall in der Medizin, 15(1), 1994, pp. 24-28
Citations number
24
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging",Acoustics
The retrospective study under report assessed the diagnostic capabilit
y of colour Doppler sonography (CDS) with measurement of the resistive
index (RI) in the long-term follow-up of patients with renal allograf
ts. 210 CDS examinations were performed in 115 patients. The time sinc
e transplantation ranged from 6 months to 22 years. The RI was correla
ted to laboratory parameters of renal allograft function (serum creati
nine, urinary protein levels and serum-cyclosporine). In 97 of 210 exa
minations, serum creatinine was elevated (> 1,5 mg % or an increase of
more then 0,3 mg % within the last 6 months). In 35 out of these exam
inations RI was > 70 %, in 62 RI was less-than-or-equal-to 70 %. Thus,
with a threshold RI of 70 %, sensitivity of the RI in the diagnosis o
f renal allograft dysfunction is 36 % and specificity 62 %, respective
ly. There was no significant difference in the RI between examinations
of allografts with normal function (68,2 % +/- 7,5 %) and those with
dysfunction (68,5 % +/- 8,5 %). Furthermore, there was no significant
correlation between the RI and any of the laboratory parameters. CDS w
ith calculation of the RI cannot differentiate in the long-term follow
-up between allografts with normal function and those with dysfunction
.