Progressive retinal atrophy of the late onset type was diagnosed in 51
Tibetan spaniels in Norway and Sweden. At the time of diagnosis they
were between three and seven years old; however, early ophthalmoscopic
changes caused by the thinning of the retina could sometimes be diffi
cult to observe because of the partial or total lack of the tapetum in
many of the dogs. The disease developed rapidly, approximately one ye
ar passing from the initial clinical signs of night blindness to compl
ete loss of vision. Twenty-four male and 27 female dogs were affected.
All the affected dogs were interrelated and could be traced back to c
ommon English ancestors. On the basis of pedigree studies, an autosoma
l recessive mode of inheritance is postulated. Information on 15 diagn
osed cases of the condition in other countries shows that the disease
may be considered a worldwide problem in the Tibetan spaniel.