Authors
Citation
S. Repgesillguth et G. Kaluza, DIFFERENCES IN ANTIGENICITY OF E2 IN SEMLIKI-FOREST VIRUS-PARTICLES AND IN INFECTED-CELLS - BRIEF REPORT, Archives of virology, 135(3-4), 1994, pp. 433-435
Citations number
13
Categorie Soggetti
Virology
Journal title
ISSN journal
03048608
Volume
135
Issue
3-4
Year of publication
1994
Pages
433 - 435
Database
ISI
SICI code
0304-8608(1994)135:3-4<433:DIAOEI>2.0.ZU;2-B
Abstract
Using six monoclonal antibodies to epitopes a-f on the glycoprotein E2
of Semliki Forest virus (SFV) we found antigenic differences between
E2 in infected cells and in virus particles, respectively, if glycosyl
ation was impaired by 2-deoxy-D-glucose or inhibited by N-methyl-1-deo
xynojirimycin. Furthermore we concluded that a conformational change o
f E2 takes place on virus budding.