DECREASED VOLUNTARY ETHANOL SELECTION IN AMYGDALA-KINDLED RATS

Kindled and control rats were exposed to either ethanol or dextrose so lutions in the limited access paradigm, a paradigm that allows access to the test solution for only 1 h each day. Limited access trials were initiated either 24 h or 30 days after the fifth stage 5 seizure had been elicited in the kindled subjects. As previously reported, increas ed voluntary ethanol selection was observed in the limited access para digm. Kindled subjects, however, ingested significantly less ethanol t han controls. This difference was found both when limited access trial s were started 24 h after the last seizure and when they were started 30 days after the last seizure. Kindled and control subjects did not d iffer in their intake of dextrose solutions.