IN-SITU HYBRIDIZATION - THEORETICAL BACKG ROUND AND PRACTICAL IMPLICATIONS

Citation
A. Bankfalvi et Kw. Schmid, IN-SITU HYBRIDIZATION - THEORETICAL BACKG ROUND AND PRACTICAL IMPLICATIONS, Der Pathologe, 15(2), 1994, pp. 76-84
Citations number
75
Categorie Soggetti
Pathology
Journal title
ISSN journal
01728113
Volume
15
Issue
2
Year of publication
1994
Pages
76 - 84
Database
ISI
SICI code
0172-8113(1994)15:2<76:IH-TBR>2.0.ZU;2-C
Abstract
In situ hybridisation is a sensitive and reliable technique for the de monstration of DNA- or mRNA-sequences on histological tissue preparati ons. This review deals with the theoretical background as well as the benefits and limitations of the method; additionally the value of in s itu hybridisation as a tool in routine diagnostic pathology is briefly described.