R. Dgani et al., SUCCESSFUL RESOLUTION OF PERSISTENT TROPHOBLASTIC DISEASE AFTER PARTIAL MOLE WITH THE EMA-CO REGIMEN, European journal of obstetrics, gynecology, and reproductive biology, 54(1), 1994, pp. 77-79
A 29-year-old nullipara with partial hydatidiform mole at 8 weeks had
pre-evacuation hCG levels of 275000 mIU/ml. Free beta-hCG levels were
measured as 3% (normal value below 4%). The patient developed persiste
nt gestational trophoblastic disease, failed to respond to methotrexat
e and actinomycin D, but has responded to combination chemotherapy wit
h EMA-CO. Such a response to EMA-CO was not reported previously.