Lh. Edmunds et al., LEFT-VENTRICULAR ASSIST WITHOUT THORACOTOMY - CLINICAL-EXPERIENCE WITH THE DENNIS METHOD, The Annals of thoracic surgery, 57(4), 1994, pp. 880-885
A method to provide left ventricular circulatory assistance without th
oracotomy was developed and implemented in 2 patients. The left atrium
is cannulated from the neck by passing a catheter across the interatr
ial septum (Dennis technique) using fluoroscopic and echocardiographic
imaging. To facilitate ambulation, the arterial catheter is connected
to the right axillary artery. Left atrial to axillary arterial now is
produced by a centrifugal pump. Two patients were perfused at 2.7 to
3.5 L/min for 5 and 6.5 days. One patient had successful coronary angi
oplasty during perfusion and remains alive 1 year later. The other pat
ient died of sepsis and anuria that preceded implementation of circula
tory assistance. The Dennis method of continuous left ventricular circ
ulatory assistance avoids thoracotomy, requires a minimal operation, i
s portable and inexpensive, uses widely available equipment, and is pa
rticularly suitable for patients in cardiogenic shock after acute myoc
ardial infarction. The method is safe and cost-effective, and merits w
ider application in selected patients.