Knowledge of the variations in coronary artery pattern is important in
the arterial switch operation for complete transposition of the great
arteries (TGA). As autopsy specimens provide the most definitive mean
s of identifying the coronary anatomy, 255 hearts with complete TGA we
re reviewed by a single pathologist. The age of the patients ranged fr
om 1 day to 34 years (mean, 2.9 years). The origin of the coronary art
eries was defined as seen by an observer looking from the pulmonary ar
tery toward the aorta. The usual pattern with the right coronary arter
y originating from the right hand sinus and the left coronary artery f
rom the left hand sinus (184 cases) and the circumflex coronary artery
arising from the right coronary artery (46 cases) accounted for 90% o
f the cases. Eleven other patterns were identified. The usual coronary
artery pattern was more prevalent in TGA with the aorta in a right an
terior or anterior position (74.8%) than in TGA with a side-by-side re
lationship of the great arteries (38.9%). In only 2 cases (0.8%) was a
n aortic intramural course of the left coronary artery identified. The
latter 2 cases confirm our belief that an aortic intramural course of
the left coronary artery or the left anterior descending coronary art
ery must be assumed when the vessel has an aberrant origin from the ri
ght sinus or when it is in intimate relationship with the commissure b
etween the right and left sinuses and courses between the great arteri
es. In the vast majority of specimens a favorable coronary artery patt
ern with regard to feasibility of the arterial switch operation was en
countered.