THE ANALYSIS OF QUANTITATIVE DERMATOGLYPHIC TRAITS IN PATIENTS WITH BRONCHIAL-ASTHMA

The question of ethiopathogenesis of bronchial asthma especially of ex trinsic type has not been clarified yet. With the aim to establish the possible genetic predisposition of this illness we analyzed 18 quanti tative dermatoglyphic traits of the digito-palmar complex of 63 patien ts suffering from extrinsic bronchial asthma with high level of IgE an d 400 phenotypicali healthy controls. Using descriptive statistics and analysis of variance it was found significantly lower number of ridge s on digits and palms in patients compared with healthy population. Us ing multivariate and univariate variance analysis statistically signif icant differences were found in manifest quantitative traits of the pa lmar dermatoglyphic complex in both sexes p<0.001 and atd angle values in females p<0.001. Canonical discriminant analysis has shown that th e best discriminators were in males b-c ridge count and in females a-b ridge counts, and other palmar variables. In males correctly is class ified 83.69% and in females 92.17% of groups. This results point out t he possibility of genetically determined predisposition of extrinsic b ronchial asthma i. e. that probably some exogenic factors which affect ed organisms during the early intrauterine growth have reflection on q uantitative dermatoglyphic traits. This results could be the basis for further researches, with the aim to estimate other analyses and also qualitative dermatoglyphic traits to clarify the ethiology of extrinsi c bronchial asthma.