THE ROLE OF LIPID-PEROXIDATION PRODUCTS A ND HEMORHEOLOGIC DISORDERS IN PATHOGENESIS AND CLINICAL RUN OF ISCHEMIC-HEART-DISEASE

Authors
MINGAZETDINOVA LN ZAKIROVA AN LANKIN VZ
Citation
Ln. Mingazetdinova et al., THE ROLE OF LIPID-PEROXIDATION PRODUCTS A ND HEMORHEOLOGIC DISORDERS IN PATHOGENESIS AND CLINICAL RUN OF ISCHEMIC-HEART-DISEASE, Terapevticeskij arhiv, 65(8), 1993, pp. 12-15
Citations number
15
Categorie Soggetti
Medicine, General & Internal
Journal title
Terapevticeskij arhiv → ACNP
ISSN journal
00403660
Volume
65
Issue
8
Year of publication
1993
Pages
12 - 15
Database
ISI
SICI code
0040-3660(1993)65:8<12:TROLPA>2.0.ZU;2-D
Abstract
Combined assessment of primary and secondary products of lipid peroxid ation, functional activity of red cells has been conducted in 130 pati ents with ischemic heart disease running different courses. Lipid pero xidation was found enhanced both in the whole blood and red blood cell s. Blood rheology got abnormal. It is shown that lipid peroxides are i nvolved in damaging erythrocytic membrane structure and function, thus promoting the progression of ischemic heart disease.