BINDING OF CU2-GNRH COMPLEXES WITH THE RAT PITUITARY RECEPTOR(, ZN2+,AND NI2+)

Authors
KOCHMAN K GAJEWSKA A KOCHMAN H KOZLOWSKI H MASIUKIEWICZ E RZESZOTARSKA B
Citation
K. Kochman et al., BINDING OF CU2-GNRH COMPLEXES WITH THE RAT PITUITARY RECEPTOR(, ZN2+,AND NI2+), Journal of inorganic biochemistry, 65(4), 1997, pp. 277-279
Citations number
18
Categorie Soggetti
Biology,"Chemistry Inorganic & Nuclear
Journal title
Journal of inorganic biochemistry → ACNP
ISSN journal
01620134
Volume
65
Issue
4
Year of publication
1997
Pages
277 - 279
Database
ISI
SICI code
0162-0134(1997)65:4<277:BOCCWT>2.0.ZU;2-4
Abstract
Complex of copper with the gonadotropin-releasing hormone, GnRH, compe ted more efficiently for the GnRH receptor than native GVRH, while com plexes of nickel with GnRH and zinc with GnRH had slightly lower affin ity. Copper ion added to the incubation mixture inhibited the busereli n binding to the receptor. (C) 1997 Elsevier Science Inc.