The authors reviewed six cases of multiple brain abscesses that were t
reated at King Khalid University Hospital (KKUH) over an eight year pe
riod. This represented 22% of the total brain abscesses treated during
the same period. The series is unusual in that the infective pathogen
s were fungi (Fonsecaea pedrosoi) in two patients (33%) and an aerobic
actinomycete (Nocardia asteroides) in one patient (16%). Two patients
treated elsewhere with antibiotics empirically for one month died at
three and 28 days following admission. The poor outcome was probably r
elated to the delay in obtaining a microbiological diagnosis and comme
ncing the appropriate antimicrobial therapy. The importance of early i
dentification of the pathogen in patients with multiple brain abscesse
s is stressed.