This study was undertaken to determine the significance of polyomaviru
s nuclear inclusions in urine cytology specimens. Thirty-two such case
s were identified and patient follow-up was instituted We have determi
ned that there is no detectable urologic damage in such patients. In a
minority of cases inclusions were found in subsequent urines but they
ultimately disappeared within 3 mo. In a minority of the patients (35
percent) there was evidence of diseases associated with immunosuppres
sion or administration of immunosuppressive drugs. (C) 1994 Wiley-Liss
, Inc.