THE PHYSICAL AND GENETIC-MAP SURROUNDING THE LYST GENE ON MOUSE CHROMOSOME-13

Authors
MISUMI DJ NAGLE DL MCGRAIL SH DUSSAULT BJ SMUTKO JS CHEN H CHARLAT O DUYK GM EBELING C BALDINI L CARLSON GA MOORE KJ
Citation
Dj. Misumi et al., THE PHYSICAL AND GENETIC-MAP SURROUNDING THE LYST GENE ON MOUSE CHROMOSOME-13, Genomics, 40(1), 1997, pp. 147-150
Citations number
21
Categorie Soggetti
Genetics & Heredity
Journal title
Genomics → ACNP
ISSN journal
08887543
Volume
40
Issue
1
Year of publication
1997
Pages
147 - 150
Database
ISI
SICI code
0888-7543(1997)40:1<147:TPAGST>2.0.ZU;2-7
Abstract
During the recent cloning of the mouse Lyst gene we developed both a h igh-resolution genetic map and a complete YAC and BAC contig of the Ly st critical region on mouse Chromosome 13. We also report the mapping of the human homologue of the mouse Lyst gene (LYST) to 1q43. These da ta are consistent with LYST being the gene for the human Chediak-Higas hi Syndrome and strengthen the synteny relationship between MMU13 and human 1q43. (C) 1997 Academic Press.