We report a case of Hutchinson-Gilford progeria syndrome (HGPS). The p
atient showed the characteristics of scleredema at the age of 2.5 mont
hs but developed all the manifestations of HGPS gradually until 10 mon
ths old. The possibility of development of HGPS should by considered i
n any case of scleredema at birth or in early infancy.