THE SYNTHESIS OF (-HEDYCARYOL, STARTING FROM NATURAL (-)-GUAIOL())

Authors
MINNAARD AJ WIJNBERG JBPA DEGROOT A
Citation
Aj. Minnaard et al., THE SYNTHESIS OF (-HEDYCARYOL, STARTING FROM NATURAL (-)-GUAIOL()), Tetrahedron, 50(16), 1994, pp. 4755-4764
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
16
Year of publication
1994
Pages
4755 - 4764
Database
ISI
SICI code
0040-4020(1994)50:16<4755:TSO(SF>2.0.ZU;2-8
Abstract
Starting from the readily available (-)-guaiol the germacrane sesquite rpene (+)-hedycaryol can be synthesized in a 7 steps reaction sequence in an overall yield of 16%. Additionally, (+)-gamma-eudesmol has been synthesized, also starting from (-)-guaiol.