B. Lorenz et al., OCULAR GROWTH IN INFANT APHAKIA - BILATERAL VERSUS UNILATERAL CONGENITAL CATARACTS, Ophthalmic paediatrics and genetics, 14(4), 1993, pp. 177-188
In a prospective study the changes in the ocular axial lengths and in
the overall refractions were examined in cases of unilateral and bilat
eral congenital cataract requiring surgery during the first year of li
fe. Measurements were taken on 18 children with unilateral and on 20 c
hildren with bilateral congenital cataract at the time of surgery and
up to eight years postoperatively. Surgery was performed via a pars pl
ana/plicata approach, and all infants were fitted with contact lenses.
In cases of unilateral cataract, the ocular axial length tended to be
superior to the age-matched values already prior to surgery. After fo
ur to eight years, one third of the eyes were clearly above normal. In
cases of bilateral cataract, the axial lengths were reduced at the ag
e of surgery in the majority of cases, and particularly in eyes that r
equired surgery during the first six months of life. The curvatures of
the contact lenses tended to remain unchanged in bilateral cataract,
and decreased by about 0.7 mm in unilateral cases. This also reflects
the high degree of microphthalmia in bilateral cases. After four to ei
ght years, the degree of microphthalmia had usually increased. The ove
rall refraction decreased significantly in unilateral and bilateral ca
taract during the first four years of life. The mean values were highe
r in bilateral than in unilateral cataract at all ages. The mean decre
ase was 15 diopters in unilateral cataract (SD +/- 5.5 dpt), and 10 di
opters in bilateral cataract (SD +/- 6 dpt). When correlating the age-
matched differences in the ocular axial lengths at the time of surgery
with the overall refractions after four to eight years, a good correl
ation was found in the unilateral cases (eight eyes), and a poor corre
lation in the bilateral cases (24 eyes). The data indicate that intrao
cular implants should not be used in bilateral cataract requiring surg
ery during the first year of life as long as there is no possibility t
o change their refraction while in place. In unilateral cases, a relat
ively accurate prediction appears possible in a small number of eight
eyes. However, an additional important correction with glasses would b
e needed before reaching the final refraction resulting in a high degr
ee of aniseiconia, and eliminating the chances for binocular vision th
at are small anyway. Furthermore, data from other authors would indica
te that the change in refraction may be much more important than expec
ted when using intraocular implants in unilateral congenital cataract
requiring surgery during the first year of life. By the use of contact
lenses, good to excellent visual functions can be achieved.