Salivary gland scintigraphy using (TCm)-T-99 sodium pertechnetate and
a 20-min dynamic data acquisition with a sialogogue at 10 min was empl
oyed as the primary imaging modality in sialadenitis in 32 patients. P
aired asymptomatic glands within the study group were used to establis
h control values for a number of computer-derived functional parameter
s. The shape of the activity-time curve was described as: H = hyperact
ive, N = normal, M = median, S = sloped, F = flat, O = obstructed. Of
seven patients who had ductal stones on plain films, two passed stones
prior to sialography and had normal curves, whole the remaining five
patients had Type O curves. Parametric evidence of gland dysfunction w
as identified in an additional seven symptomatic glands, six being hyp
eractive; histology identified an acute inflammatory infiltrate in the
only excised gland in this group. Glandular hypofunction was identifi
ed in one case, in which histology revealed extensive fibrosis and gla
ndular atrophy. Type M and S curves were found in 28 glands, 75% of wh
ich were asymptomatic. Only one gland was indicated as hypoactive by c
alculated parameters, and this showed a Type S curve. Scintigraphy and
plain films represent the least invasive and, we feel, the most suita
ble primary method of investigating sialadenitis. Conventional contras
t sialography may be reserved for cases with no identifiable stone but
an obstructed curve. The use of functional parameters and curve morph
ology to determine gland dysfunction other than obstruction is non-spe
cific, probably insensitive and is unlikely to alter clinical manageme
nt. We propose an algorithm for the investigation of sialadenitis.